By Flossie Wong-Staal, Robert C. Gallo
This reference describes the newest advances within the improvement and layout of an HIV preventive vaccine-detailing the pathogenesis and genetic variability of HIV an infection for the development of molecular and healing innovations to lessen the development and transmission of AIDS. With contributions by way of universally well-known gurus within the box, AIDS Vaccine study discusses
Read or Download AIDS Vaccine Research PDF
Best hematology books
Blood transfusion is a vital a part of glossy health and wellbeing care. Used competently, it may be a life-saving intervention. beside the point use can endanger existence a result of capability possibility of acute or behind schedule problems, together with the transmission of infectious brokers, equivalent to HIV, hepatitis viruses, syphilis, malaria and Chagas ailment.
Continual Myeloid Leukemia (CML) continues to be a key version for the enhanced knowing of the pathophysiology of a malignancy at a molecular point and has been utilized by researchers to boost various treatments and healing overview equipment. This concise, readable consultant assembles and synthesizes the newest advancements and tendencies within the therapy of CML and gives an authoritative and handy precis of the newest development in imatinib trials, the molecular tracking of CML responses, and the engineering of recent treatments to beat resistance and enhance sufferer care.
Via proposing the most recent technological advances and transforming into nationwide and overseas law, this new publication explores cutting-edge advancements within the demanding box of tissue and cellphone processing. It presents a consultant to more straightforward and more secure perform in operational rules of upkeep, decontamination, and sterilization.
Disseminated intravascular coagulation is a devastating syndrome characterized via the systemic activation of frequent activation of the coagulation cascade and thrombosis, that could bring about serious bleeding and should result in organ failure. fresh experiences have proven that the occurrence of DIC is lowering, particularly in males.
- Hematologic Malignancies: Methods & Techniques
- Sjögren’s Syndrome in Clinical Practice
- Rare Hematological Malignancies (Cancer Treatment and Research)
- Primary Hematology
- HIV-associated Hematological Malignancies
Extra info for AIDS Vaccine Research
Cytokines that enhance viral replication (ϩ), inhibit viral replication (Ϫ), and enhance or inhibit viral replication depending upon the conditions (ϩ/Ϫ) are shown. that have been reported to upregulate HIV replication in vitro include IL-1β, IL-2, IL-3, IL-6, IL-7, IL-12, IL-15, IL-18, TNF-α, TNF-β, and the colony-stimulating factors (CSF) macrophage (M)–CSF and granulocyte-macrophage (GM)–CSF (reviewed in Ref. 283; see also Refs. 308–313). IFN-α, IFN-β, and IL-16 (275,314,315) are primarily suppressors of HIV production, whereas other cytokines, such as IL-4 (316,317), IL-10 (318–321), IL-13 (316), IFN-γ (322,323), Immunopathogenesis of HIV Infection 29 and TGF-β (324,325), reduce or enhance viral replication depending on the infected cell type and the culture conditions.
A. Axel. 1986. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell 47:333–348. 5. A. Berger. 1995. Fusogenic selectivity of the envelope glycoprotein is a major determinant of human immunodeﬁciency virus type 1 tropism for CD4ϩ T-cell lines vs. primary macrophages. Proc Natl Acad Sci USA 92:9004–9008. 6. C. A. Berger. 1996. Cell type-speciﬁc fusion Immunopathogenesis of HIV Infection 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 41 cofactors determine human immunodeﬁciency virus type 1 tropism for Tcell lines versus primary macrophages.
Science 225:59–63. 3. , E. Champagne, S. Chamaret, J. Gruest, D. Guetard, T. -C. Gluckman, L. Montagnier. 1984. T-lymphocyte T4 molecule behaves as receptor for human retrovirus LAV. Nature 312:767–768. 4. G. S. R. A. A. Axel. 1986. The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain. Cell 47:333–348. 5. A. Berger. 1995. Fusogenic selectivity of the envelope glycoprotein is a major determinant of human immunodeﬁciency virus type 1 tropism for CD4ϩ T-cell lines vs.
AIDS Vaccine Research by Flossie Wong-Staal, Robert C. Gallo